The new Mercedes-Benz CLS meets the highest standards with regard to safety, comfort, agility, and design, and was also analysed comprehensively in terms of its environmental impact over the entire lifecycle.
Over the entire life cycle of the CLS 350 d 4MATIC (combined fuel consumption (diesel): 5.8–5.6 l/100 km; combined CO₂ emissions: 156–148 g/km*) the life cycle inventory analysis yields an environmental input of approximately 50 tons of CO₂  and around 75 kilograms NOx .
 Status environmental certificate/certificated values: 2018
In the base variant of the CLS, a total of 132 components with an overall weight of 53.5 kilograms can be manufactured partly from high-quality recycled plastics. Typical areas of use are wheel arch linings, cable ducts and underbody panels, which consist for the most part of polypropylene.
With the material Dinamica® a high-quality secondary raw material is now also used in the interior of the new CLS. Dinamica® is a microfiber made of recycled polyester and water-borne polyurethane. The recycled polyester contained in Dinamica® derives e.g. from textiles and PET bottles.
In automotive production, the use of renewable raw materials is concentrated primarily in the vehicle interior. Established natural materials such as flax and cellulose fibres, wool, cotton and natural rubber are also used, of course, in series production of the CLS.
In the base variant of the new CLS, a total of 86 components with an overall weight of 32.2 kilograms are made using natural materials.
Since 2016 all new Mercedes-Benz cars are awarded with the Seal of Quality from the European Centre for Allergy Research Foundation (ECARF). The ECARF Seal of Quality is used by ECARF to designate products that have been scientifically tested and proven to be suitable for allergy sufferers.